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Ara-290, Cibinetide · How it works
Small nerve fibre regrowth
Small nerve fibres carry pain, temperature and the automatic signals to the gut, bladder, heart and sweat glands. Through the repair receptor, Ara-290 supports these fibres to regrow. In the cornea, where nerves can be counted directly, fibre area rose in 28 days. GAP-43, the marker of growing nerve tips, rose in the skin.
Sources
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- ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density (Abstract · checked 2026-10-13)
- Cibinetide: sarcoidosis small nerve fibre trial (Culver and colleagues · 2017 · Published abstract · checked 2026-10-08)