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Cagrilintide and Semaglutide Blend · How it works
GLP-1: the hunger dial
The semaglutide half is a long-acting GLP-1 analogue. It acts on GLP-1 receptors in the hypothalamus and brainstem to quiet hunger and food noise. It slows the stomach and makes the pancreas release insulin only when glucose is high. Semaglutide reaches deep appetite centres that most hormones cannot.
Sources
Read the original sources
- Discovery of the once-weekly GLP-1 analogue semaglutide, Lau 2015, J Med Chem (Abstract · checked 2026-10-13)
- Semaglutide lowers body weight in rodents via distributed neural pathways (2020 · Abstract; rodent mechanism · checked 2026-10-13)