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GHRP-6 Acetate
The story
In 1984 Cyril Bowers at Tulane University and Frank Momany designed GHRP-6 from shapes of met-enkephalin and showed it released growth hormone straight from the pituitary. Nobody knew what receptor it hit until Merck cloned the GHS receptor in 1996, and in 1999 Kojima and Kangawa in Japan found the body's own key, ghrelin. In Belgrade, Vera Popovic and Sandra Pekic made GHRH plus GHRP-6 a standard test of growth hormone reserve across Eastern Europe. In Havana, Jorge Berlanga-Acosta's group at the Center for Genetic Engineering and Biotechnology showed GHRP-6 protects heart, liver, gut and brain from injury, and measured how it moves through the human body.
Sources
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- On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone (Abstract · checked 2026-10-13)
- A receptor in pituitary and hypothalamus that functions in growth hormone release (Abstract · checked 2026-10-13)
- Ghrelin is a growth-hormone-releasing acylated peptide from stomach (Abstract · checked 2026-10-13)
- Effect of obesity and morbid obesity on the GH secretion elicited by the combined GHRH + GHRP-6 test (Turkey and Serbia) (Abstract · checked 2026-10-13)
- Synthetic Growth Hormone-Releasing Peptides (GHRPs): A Historical Appraisal of the Evidences Supporting Their Cytoprotective Effects (Abstract · checked 2026-10-13)
- Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers (Cuba) (Abstract · checked 2026-10-13)