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IGF-1 LR4
What it is
IGF-1 LR4 belongs to the long-R3 family of IGF-1 analogs: human IGF-1 with a front extension and an amino acid swap near the start that cuts binding to IGF-binding proteins. LR4 is the name it is sold under; it is handled and dosed like LR3. Freed from binding proteins, it reaches the IGF-1 receptor on muscle, bone, cartilage and skin and acts for hours. It comes in a larger 1 mg vial.
Sources
Read the original sources
- Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency (Abstract · checked 2026-10-13)
- Long R3 IGF-I, Repligen identity and cell-culture use (Identity and cell-culture sections · checked 2026-10-13)