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Kisspeptin-10
What it is
Kisspeptin-10 is the ten residue active fragment of the kisspeptin family, the common short form of a signal your own hypothalamus makes. Its receptor is KISS1R, once called GPR54. The longer kisspeptin-54, the original metastin, is the same signal in a longer wrapper and behaves differently in the body: given under the skin it lasts around half an hour against roughly four minutes for the ten residue form after a vein dose. They are not interchangeable, and a result from one does not transfer to the other. This is a hormone-system switch, not a tissue repair peptide.
Sources
Read the original sources
- Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor (Abstract · checked 2026-10-13)
- Kisspeptin-10: short human hormone studies (George and colleagues · 2011 · Published abstract · checked 2026-10-08)
- Direct comparison of the effects of intravenous kisspeptin-10, kisspeptin-54 and GnRH on gonadotrophin secretion in healthy men (Summary · checked 2026-10-13)