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KLOW Blend · How it works
KPV: inflammation off
KPV is Lys-Pro-Val, the calming tail of the hormone alpha-MSH. It rides the PepT1 transporter into inflamed cells and blocks NF-kB, the master switch for inflammatory genes. Signals such as IL-6 and TNF-alpha fall. It ends the inflamed phase so the repair peptides can work.
Sources
Read the original sources
- Targeting melanocortin receptors as a novel strategy to control inflammation (Abstract · checked 2026-10-13)
- KPV: cell signals and mouse colitis (Dalmasso and colleagues · 2008 · Published abstract · checked 2026-10-08)
- Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease (Abstract · checked 2026-10-13)