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KPV, Lysine-Proline-Valine
How it works
KPV carries alpha-MSH's calming action into inflamed cells through PepT1 and switches off NF-kB.
Sources
Read the original sources
- Targeting melanocortin receptors as a novel strategy to control inflammation (Abstract · checked 2026-10-13)
- The neuroimmunomodulatory peptide alpha-MSH (Ichiyama, Japan) (Abstract · checked 2026-10-13)
- Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease (Abstract · checked 2026-10-13)
- KPV: cell signals and mouse colitis (Dalmasso and colleagues · 2008 · Published abstract · checked 2026-10-08)
- Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis (Abstract · checked 2026-10-13)