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Melatonin
How it is taken
The schedule
| Route | Injection under the skin |
|---|---|
| Amount to start | 0.5 mg |
| How often | Once a night |
| When | 30 to 60 minutes before bed |
| Steps up and down |
|
| How long | 8 weeks |
| Cycle | 8 weeks on, 1 to 2 weeks off |
| Mixing | Add 2 mL bacteriostatic water to the 10 mg vial (5 mg per mL). Swirl gently until clear, never shake. |
| Storage | Before mixing: cool and dark. After mixing: fridge, in the dark, use within 28 days. |
Melatonin is injected under the skin once a night, 30 to 60 minutes before bed. Start at 0.5 mg and go to 1 mg from the second week if needed. Run it for 8 weeks.
Dose calculator
Change any box to work out a different amount.
How it works: strength per mL = vial strength ÷ water added. mL to draw = dose ÷ strength per mL. Units on a U-100 insulin syringe = mL × 100 (1 mL = 100 units). Doses per vial = vial strength ÷ dose. 1 mg = 1000 mcg.
Your personal schedule is set after we review your survey.
Sources
Read the original sources
- Melatonin receptors: role on sleep and circadian rhythm regulation. (Dubocovich · 2007 · Abstract; full methods not assumed · checked 2026-10-13)
- Melatonin increases both life span and tumor incidence in female CBA mice (Summary · checked 2026-10-13)
- Geroprotectors and carcinogenesis, a lecture (Reviews on Clinical Pharmacology and Drug Therapy, 2004, in Russian) (Abstract · checked 2026-10-13)