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MOTS-c · How it works
Insulin sensitivity
Insulin resistance means muscle stops taking glucose from the blood. MOTS-c restores glucose uptake in muscle and reverses diet-driven insulin resistance and weight gain in mice. It also prevents the age-related rise in insulin resistance. Blood sugar settles from the muscle side.
Sources
Read the original sources
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. (2015 · Abstract; full methods not assumed · checked 2026-10-13)