Melanotan I, MT1
Why it is for you
This fits one root-cause picture precisely: skin that does not make enough dark pigment to defend itself. That is pale skin that burns and never tans, skin that reacts painfully to light, or skin that has lost its pigment in patches. It is the wrong tool for an existing tan, for pigment that is too dark or uneven, and for anybody whose moles are numerous, irregular or changing, because this molecule speaks to exactly the cells those moles are made of. It pairs with ultraviolet light therapy where pigment is being brought back to white patches, and with the plain unglamorous work of sunscreen and shade, since more pigment is a shield and not a licence. Before it goes anywhere near a person, a dermatologist should have mapped and photographed their moles, and this one is non-negotiable.
Sources
Read the original sources
- Afamelanotide: erythropoietic protoporphyria (Langendonk and colleagues · 2015 · Published abstract · checked 2026-10-08)
- Afamelanotide and narrowband UV-B phototherapy for the treatment of vitiligo (Summary · checked 2026-10-13)
- Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review (Abstract · checked 2026-10-13)
- MC1R: front and center in the bright side of dark eumelanin and DNA repair (Abstract · checked 2026-10-13)