NAD+ · How it is taken

Going up and down

Week 1 is 25 mg a day to let the body adjust. Week 2 is 50 mg. From week 3 the working dose is 100 mg. If the flush or nausea is strong, stay at the lower step one more week before going up.

Sources

Read the original sources

IV NAD+: metabolic pilot (Grant and colleagues · 2019 · Published abstract · checked 2026-10-08)
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults (Summary · checked 2026-10-13)
The human NAD metabolome: Functions, metabolism and compartmentalization. (Nikiforov · 2015 · Abstract; full methods not assumed · checked 2026-10-13)