NAD+ · How it is taken

Cycles and breaks

Run 8 weeks on, then take 4 weeks off. For upkeep after the first round, many people drop to 100 mg two or three times a week. Repeat a full round two or three times a year.

Sources

Read the original sources

IV NAD+: metabolic pilot (Grant and colleagues · 2019 · Published abstract · checked 2026-10-08)
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults (Summary · checked 2026-10-13)
The human NAD metabolome: Functions, metabolism and compartmentalization. (Nikiforov · 2015 · Abstract; full methods not assumed · checked 2026-10-13)