PNC-27

How it works

It docks on HDM-2 displayed in a cancer cell's membrane, assembles into pores, and the cell bursts, with the mitochondria failing alongside. Open a pathway to follow the body process.

Sources

Read the original sources

PNC-27: cancer cell membrane study (2010 · Published abstract · checked 2026-10-08)
PNC-27 binds HDM-2 in a p53 peptide-like structure, induces selective membrane-pore formation and leads to cancer cell lysis (Abstract · checked 2026-10-13)

HDM-2 in the membrane, which normal cells do not showOpen It makes a pore, and the cell burstsOpen The shape it adopts on bindingOpen A second hit on the mitochondriaOpen