Crow's feet and the eye corners

The skin at the outer eye is thin and it creases every time you smile or squint. This is where the hexapeptide family was measured most closely, with roughness on silicone replicas of the skin falling over four weeks of twice daily use. The lines soften rather than vanish, because the fold is still being made each day. Thin skin also means a topical has less distance to travel to reach the layer that matters.