In people

People who use it describe a softening rather than a freeze. The face still moves exactly as it did, and the change shows in how the skin folds while it moves and how much of that fold is still there at rest. On measured skin, surface roughness drops and wrinkle depth falls, with the hexapeptide version reaching up to 30 percent shallower lines across 30 days of twice daily use at 10 percent, and about half of users in Chinese skin judged to have improved against none on placebo. It is gentle on the skin, with no irritation reported at high amounts in the original work. The effect builds while you use it and fades back when you stop, because the muscle underneath never changed.