SS-31, Elamipretide · How it works

Cristae and ATP

Cristae are the folds of the inner membrane where energy is made. SS-31 keeps their shape. Electron transport runs smoothly and ATP output recovers. Damaged, energy-starved mitochondria are recharged.

Sources

Read the original sources

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. (Szeto · 2014 · Abstract; full methods not assumed · checked 2026-10-13)
The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin. (2013 · Abstract; full methods not assumed · checked 2026-10-13)