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Survodutide
How it works
Survodutide pairs glucagon, which burns fat inside the liver and raises energy use, with GLP-1, which quiets hunger and keeps blood sugar steady.
Sources
Read the original sources
- BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy. (Zimmermann · 2022 · Abstract; full methods not assumed · checked 2026-10-13)
- Shared mechanistic pathways of glucagon signalling in obesity and fatty liver, Neff 2025, Diabetes Obes Metab (Abstract · checked 2026-10-13)
- Glucagon and alpha cells, a new target in diabetes, 2013, Diabetes Mellitus (Russia) (Summary · checked 2026-10-13)
- Semaglutide lowers body weight in rodents via distributed neural pathways (2020 · Abstract; rodent mechanism · checked 2026-10-13)
- The mechanism of action of oxyntomodulin in the regulation of obesity, Wynne 2010 (Abstract · checked 2026-10-13)
- GLP-1, glucagon and the GLP-1/glucagon co-agonist oxyntomodulin after bariatric surgery, 2025, Diabetes Mellitus (Russia) (Summary · checked 2026-10-13)