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Tirzepatide · How it is taken
The schedule
One injection each week on the same day, at any time of day, with or without food. Weeks 1 to 4: 2.5 mg. Weeks 5 to 8: 5 mg. Weeks 9 to 12: 7.5 mg. Weeks 13 to 16: 10 mg. Weeks 17 to 20: 12.5 mg. Week 21 on: up to 15 mg. Many people reach their goal on 5 to 10 mg and stay there.
Sources
Read the original sources
- SURMOUNT-1: tirzepatide and obesity (Jastreboff and colleagues · 2022 · Published abstract · checked 2026-10-08)
- Tirzepatide protocol, Peptide Dosing Protocols (Full text · checked 2026-10-13)