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Tirzepatide · How it is taken
Going up and down
Step up only when the current dose feels easy and weight loss has slowed. If nausea or fullness is strong, stay on the same dose another 4 weeks before stepping up. Once the goal weight is reached, the dose is lowered step by step, for example 15 to 10 to 5 mg over several months, to hold the result while eating and training habits take over.
Sources
Read the original sources
- SURMOUNT-1: tirzepatide and obesity (Jastreboff and colleagues · 2022 · Published abstract · checked 2026-10-08)
- Tirzepatide protocol, Peptide Dosing Protocols (Full text · checked 2026-10-13)