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Vesugen
The story
Vesugen was designed at Vladimir Khavinson's Institute of Bioregulation and Gerontology in St Petersburg, from the amino acid makeup of a peptide extract taken from blood vessel walls. It was built to restore vessels in older people with atherosclerosis and poor circulation. St Petersburg labs showed it restarts division in aged endothelial cells by binding the promoter of the Ki-67 gene. Later work found it also guides stem cells toward nerve cells and protects synapses in Alzheimer models.
Sources
Read the original sources
- Vesugen: cell growth and molecular modelling (Khavinson and colleagues · 2014 · Published abstract · checked 2026-10-08)
- Molecular aspects of vasoprotective peptide KED activity during atherosclerosis and restenosis (Abstract · checked 2026-10-13)
- Peptide KED: molecular-genetic aspects of neurogenesis regulation in Alzheimer's disease (Abstract · checked 2026-10-13)
- Effect of short peptides on neuronal differentiation of stem cells (Abstract · checked 2026-10-13)