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Vilon
The story
Vilon came out of Vladimir Khavinson's Institute of Bioregulation and Gerontology in St Petersburg, where Khavinson and Vladimir Morozov first made Thymalin from calf thymus in the 1970s. Searching for the active core, the team built the dipeptide Lys-Glu. In 2000 Khavinson and Vladimir Anisimov showed that lifelong Vilon slowed biological ageing, reduced spontaneous tumours and lengthened life in mice. Later work in Moscow and St Petersburg showed it drives thymus cell growth and turns on SIRT1 in human stem cells.
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- A synthetic dipeptide Vilon (L-Lys-L-Glu) inhibits growth of spontaneous tumors and increases life span of mice (Abstract · checked 2026-10-13)
- Effect of Vilon on biological age and lifespan in mice (Abstract · checked 2026-10-13)
- Vilon and Epithalon: cultured mouse thymocytes (2002 · Published abstract · checked 2026-10-08)
- KE peptide regulates SIRT1, PARP1, PARP2 gene expression and protein synthesis in human mesenchymal stem cells aging (Abstract · checked 2026-10-13)